The disease (relatively rare) occurs at any age (from 4.5 to 75 years), equally common in men and women. Etiology and pathogenesis have not been established. There are different points of view on the possible mechanisms of development of dermatosis. Some authors consider ashy dermatosis a consequence of pyridium pills process in the skin, others suggest a toxic-allergic nature (cases that developed after the use of pyridium drugs, cosmetics, food products are described). The role of endocrine disorders and immune shifts is discussed. There is an opinion that dermatosis is a variant of the pigmented form of lichen planus. Do not exclude the polyetiological nature of the disease.
The main clinical sign of the disease is multiple ash-gray pigment spots, which may appear suddenly and manifest as multiple rashes or develop slowly from one or more elements. Spots with a diameter of several millimeters to 2 - 10 cm, not merging with each other, slate or dirty brown in color, sometimes with some blueness or with a slight bluish tint, not itchy, not flaky, not changing with friction. In the early stage of the disease, mild marginal erythema (active edge) is detected. Rashes are localized on the neck, shoulders, back (including over the spinous processes of the vertebrae), less often - on the front surface of the trunk, thighs and on the face (on the cheeks).
Mucous membranes are not affected. The general condition is not violated. Pathology from the internal organs is not detected. There are no subjective complaints. Pigmentation or hypopigmentation may be present simultaneously on the same spots. The course of the disease is long, but in some cases it resolves spontaneously in a period of 2-3 months to buy pyridium online. Differential diagnosis should primarily be carried out with a fixed drug rash, using data from the anamnesis, the clinical course of the disease and the histological picture. Ash dermatosis should also be differentiated from spotted melasma, some forms of lichen planus, pigment incontinence, leprosy, spotted mastocytosis.
In the treatment of ash dermatosis, drugs of different pharmacological groups were used, for example, antibiotics, glucocorticosteroids, sulfones, antimalarial, non-steroidal antiphlogistics, which turned out to buy phenazopyridine online. Cases of resolution of the rash after sanitation of foci of chronic infection are described. It is recommended to use outdoor sunscreen. Systemic photoprotective agents include cyanocobalamin, aminoquinol, hydroxychloroquine. As local protective agents, creams are used, which include titanium dioxide, derivatives of para-aminobenzoic acid, zinc oxide.
Recently, clofazimine has been used to treat ash-gray dermatosis. Clofazimine is an anti-inflammatory and antimicrobial drug. Initially, the drug was developed for the treatment of tuberculosis, but proved to be quite effective in the treatment of ash-gray dermatosis. The drug is administered in an amount of phenazopyridine 200 mg pills daily for patients weighing more than 40 kg, and at the same dose every other day for patients whose weight does not reach 40 kg. Treatment with clophyzimine is quite long. At the indicated dose, the drug is administered for 3 months, then the dose is reduced to 400/200 mg per week, respectively.
25 unusual diseases that defy scientific explanation. Their symptoms vary. from simple rashes to bone deformities. Some patients of the disease cause a lot of discomfort, while others live safely with them and do not notice any inconvenience. Below is a list of the most unusual diseases known to date. Foreign accent syndrome is an external disorder due to which a person suddenly begins to distort speech turns, as foreigners usually do. Scientists suggest that the symptoms may be associated with a stroke or multiple sclerosis. But this theory has no evidence.
People who complain of regular bouts of acute pain in the mucous membranes, on the tongue, lips, gums, cheeks, may be victims of burning mouth syndrome. Where does the disease come from, and how to treat it, experts inwhat they don't know. There is an opinion that laughter is the best medicine. But it is not entirely correct. There are cases when people died of laughter. Sometimes too strong an attack of fun can lead to suffocation and cardiac arrest. The earth is 70% water, about the same amount of liquid in the human body. Therefore, people with allergies to water or aquatic urticaria have a hard time. Danger awaits them everywhere. When in contact with water, the skin of people with this diagnosis begins to become covered with a small red rash.
Specialists are working hard to find out the causes of pyridium pills. You can sin on genes, viruses, birth trauma and many other factors, but so far scientists have not been able to reach anything concrete. Schizophrenia is still an incurable severe chronic mental disorder that affects the thoughts, feelings and behavior of the patient.
Patients with this diagnosis become aroused for no apparent reason and may remain in this state for months. Of course, this affects the quality of life and the emotional state of the patient. This is a very interesting disease, because of which patients suddenly begin to feel that either they themselves, or the room in which they are located, is increasing or decreasing in size. Doctors are inclined to believe that factors such as traumatic brain injury, epilepsy, and frequent migraines cause the syndrome.
This is a neurological disease that prevents a person from moving facial muscles. That is, patients are unable to smile, frown, look sideways. Doctors do not know the exact cause of the development of phenazopyridine, but sin on a genetic predisposition and environmental factors. This is a relatively new disease that was first diagnosed in Britain. In calves suffering from an unknown ailment, the temperature rose and healthy and unharmed skin began to bleed. Unfortunate people with such a diagnosis, as a rule, die. Scientists are actively working on studying the causes and possible methods of treating the syndrome.
